Package | Dosage | Price | Price per Dose | |
---|---|---|---|---|
Dosage: 500mg | ||||
180 pill | 500mg | $510.38 | $2.84 | |
120 pill | 500mg | $363.64 | $3.03 | |
90 pill | 500mg | $287.08 | $3.19 | |
60 pill | 500mg | $213.71 | $3.56 | |
30 pill | 500mg | $143.53 | $4.79 | |
Dosage: 1000mg | ||||
180 pill | 1000mg | $574.18 | $3.19 | |
120 pill | 1000mg | $411.49 | $3.43 | |
90 pill | 1000mg | $347.69 | $3.86 | |
60 pill | 1000mg | $258.37 | $4.31 | |
30 pill | 1000mg | $153.10 | $5.10 |

Ranolazine Description
Introduction to Ranolazine
Ranolazine is a medication primarily used to treat chronic angina, a condition characterized by chest pain resulting from reduced blood flow to the heart. It belongs to a unique class of drugs that work differently from traditional anti-anginal medications. Ranolazine helps improve the quality of life for many patients by reducing the frequency and severity of angina episodes.
Mechanism of Action
This medication operates by selectively inhibiting late sodium currents in cardiac cells. During ischemic conditions, these currents tend to become excessive, leading to increased calcium overload within the heart muscle. By blocking these currents, ranolazine decreases calcium levels inside the cells, which in turn reduces myocardial oxygen consumption. This process helps alleviate chest pain and improves the heart’s efficiency without significantly affecting blood pressure or heart rate.
Effectiveness and Clinical Use
Many patients with chronic angina find relief with ranolazine, especially when other treatments have not provided satisfactory results. Clinical studies have shown that the medication can help reduce symptoms and improve exercise tolerance. It is often prescribed as part of a comprehensive management plan, which may include lifestyle modifications and other medications like nitrates or beta-blockers.
Advantages Over Traditional Medications
One of the notable benefits of ranolazine is that it does not significantly impact blood pressure or heart rate, making it a suitable option for patients with particular cardiovascular profiles. It also tends to have a favorable side effect profile when used appropriately. Its unique mechanism offers an alternative pathway to manage angina, especially for patients intolerant to other drugs.
Possible Side Effects and Precautions
While generally well-tolerated, ranolazine can cause side effects in some individuals. Common issues include dizziness, headache, constipation, and nausea. Rarely, it may lead to more serious effects such as QT prolongation, which affects the heart's electrical activity and can increase the risk of arrhythmias. Patients with pre-existing liver or kidney problems should use the medication cautiously and under medical supervision. It’s also important to inform healthcare providers about any other medications being taken, as ranolazine can interact with drugs like certain antifungals and antibiotics.
Usage Guidelines
The medication is typically prescribed in small, gradually increasing doses to minimize side effects. It is usually taken twice daily, with or without food. Patients should adhere strictly to their healthcare provider’s instructions and report any adverse reactions promptly. Regular monitoring through clinical assessments may be necessary to ensure optimal results and safety.
Summary
Ranolazine offers a valuable option for managing chronic angina, especially when traditional therapies are insufficient or not tolerated. Its unique mode of action and relatively mild side effect profile make it a popular choice among clinicians and patients alike. Like all medications, it should be used responsibly under medical supervision, with attention to possible interactions and contraindications.