| Package | Dosage | Price | Price per Dose | |
|---|---|---|---|---|
| Dosage: 15mg | ||||
| 360 pill | 15mg | $219.99 | $0.61 | |
| 180 pill | 15mg | $118.99 | $0.66 | |
| 120 pill | 15mg | $85.99 | $0.72 | |
| 90 pill | 15mg | $68.99 | $0.77 | |
| 60 pill | 15mg | $49.99 | $0.83 | |
| 30 pill | 15mg | $28.99 | $0.95 | |
| Dosage: 30mg | ||||
| 360 pill | 30mg | $377.99 | $1.05 | |
| 180 pill | 30mg | $204.99 | $1.14 | |
| 120 pill | 30mg | $148.99 | $1.24 | |
| 90 pill | 30mg | $118.99 | $1.32 | |
| 60 pill | 30mg | $84.99 | $1.41 | |
| 30 pill | 30mg | $46.99 | $1.56 | |
| 10 pill | 30mg | $17.99 | $1.75 | |
Pioglitazone Description
Overview of Pioglitazone
Pioglitazone is a medication primarily prescribed to help manage blood sugar levels in individuals with type 2 diabetes mellitus. It belongs to a class of drugs known as thiazolidinediones, which work by improving the body's sensitivity to insulin. This action helps the body use insulin more effectively, resulting in better control of blood glucose levels. Pioglitazone is often used in combination with other diabetic medications or lifestyle modifications such as diet and exercise.
How Pioglitazone Works
The primary mechanism of pioglitazone involves activating a receptor called PPAR-gamma. Activation of this receptor influences the genes involved in glucose and lipid metabolism. By modulating these genes, pioglitazone enhances the body's response to insulin, leading to decreased insulin resistance. This can help reduce fasting blood glucose levels and improve overall glycemic control. It also has some beneficial effects on lipid profiles, often increasing HDL cholesterol and reducing triglycerides.
Benefits of Using Pioglitazone
Many patients find relief in the consistent blood sugar control they achieve with pioglitazone. It is particularly effective in patients who struggle with insulin resistance. In addition, pioglitazone’s ability to positively influence lipid levels can be advantageous for diabetic patients who are at risk of cardiovascular problems. This medication can also help prevent the progression of diabetes-related complications if used as part of a comprehensive treatment plan.
Possible Side Effects and Precautions
Like all medications, pioglitazone can cause side effects. Some common ones include weight gain, edema, and dizziness. Less frequently, it may lead to elevated liver enzymes or fluid retention, which warrants regular monitoring. In rare cases, pioglitazone has been associated with an increased risk of heart failure, especially in individuals with existing cardiac problems. There have also been concerns about the potential risk of bladder cancer, so it is essential for healthcare providers to evaluate individual risks before prescribing this drug.
Usage and Dosage
Pioglitazone dosage varies depending on the patient's condition and response to the treatment. It is typically administered once daily, with or without food. Physicians usually start with a low dose to monitor tolerability and then adjust accordingly. Patients are advised to adhere strictly to their healthcare provider’s instructions and attend regular check-ups to monitor for potential side effects or adverse reactions.
Conclusion
Pioglitazone remains a valuable option for managing type 2 diabetes, especially in patients needing improved insulin sensitivity. Its dual benefits on blood sugar control and lipid profile make it a noteworthy choice in comprehensive diabetes care. However, due to potential side effects, proper medical supervision is crucial to ensure safe and effective use. Patients should be aware of the importance of routine monitoring and lifestyle adjustments alongside medication therapy.