Package | Dosage | Price | Price per Dose | |
---|---|---|---|---|
Dosage: 2,5 mg | ||||
270 pill | 2,5 mg | $258.37 | $0.96 | |
180 pill | 2,5 mg | $208.93 | $1.16 | |
Dosage: 2,5mg | ||||
120 pill | 2,5mg | $191.38 | $1.60 | |
90 pill | 2,5mg | $186.60 | $2.07 | |
60 pill | 2,5mg | $143.53 | $2.39 | |
30 pill | 2,5mg | $79.73 | $2.66 | |
10 pill | 2,5mg | $31.88 | $3.19 |
Letrozole Description
What Is Letrozole?
Letrozole is a medication primarily used in the treatment of hormone receptor-positive breast cancer in postmenopausal women. It belongs to a class of drugs known as aromatase inhibitors. These drugs work by blocking the enzyme aromatase, responsible for converting androgens into estrogen in the body. By reducing estrogen levels, Letrozole helps to slow or stop the growth of estrogen-dependent breast tumors. Besides its oncological use, Letrozole is sometimes prescribed off-label for other hormonal imbalances or fertility treatments, though its primary indication remains breast cancer management.
How Does Letrozole Work?
The mechanism of Letrozole focuses on inhibiting aromatase activity. Aromatase is an enzyme found in various tissues, including the ovaries, adipose tissue, and the adrenal glands. In postmenopausal women, peripheral tissues become the main source of estrogen production. By inhibiting aromatase, Letrozole significantly lowers estrogen levels in the bloodstream. This suppression diminishes the proliferative advantage that estrogen provides to certain types of breast cancer cells. As a result, Letrozole can effectively reduce tumor growth and help prevent recurrence when used as part of a comprehensive treatment plan.
Benefits and Effectiveness
Many patients have reported positive outcomes with Letrozole. It is well-tolerated by most, and its efficacy in reducing estrogen levels contributes to improved survival rates for women with hormone-sensitive breast cancer. Clinical studies have demonstrated that Letrozole can be more effective than some older hormone therapies, especially in postmenopausal women. It is often used as an adjuvant therapy following surgery, radiation, or chemotherapy. Additionally, some women use Letrozole during early stages of hormone therapy, with the goal of decreasing the risk of cancer recurrence.
Potential Side Effects and Risks
While Letrozole offers significant benefits, it can also cause side effects. Common issues include hot flashes, joint pain, fatigue, and sweating. Some women may experience bone thinning or osteoporosis over long-term use, necessitating monitoring and potential supplementation. Mood changes, nausea, and headaches have also been reported. Rare but serious risks include liver problems and allergic reactions. It is crucial to discuss any concerns with a healthcare provider. Regular monitoring helps manage side effects, ensuring the safe use of the medication.
Usage and Dosage
Letrozole is typically prescribed in tablet form, with common dosages ranging from 2.5 mg once daily. The exact dosage and duration depend on the individual’s condition and how they respond to treatment. It is important to follow the healthcare provider's instructions carefully. Patients are advised not to stop or alter their medication without consulting their doctor. During treatment, regular check-ups and hormone level assessments are recommended to evaluate effectiveness and adjust treatment if needed.
Availability and Purchasing
Letrozole is available through licensed pharmacies, including online platforms that adhere to quality standards. When purchasing online, it is essential to ensure the source is reputable and authorized to sell medications. Proper packaging, clear instructions, and authentic medication are vital to ensure safety. Patients should always verify the authenticity of the product and consult with a healthcare provider before starting treatment, especially when considering online pharmacies.