Package | Dosage | Price | Price per Dose | |
---|---|---|---|---|
Dosage: 2,5mg | ||||
360 pill | 2,5mg | $183.99 | $0.51 | |
180 pill | 2,5mg | $98.99 | $0.55 | |
120 pill | 2,5mg | $70.99 | $0.59 | |
90 pill | 2,5mg | $57.99 | $0.64 | |
60 pill | 2,5mg | $41.99 | $0.70 | |
30 pill | 2,5mg | $24.99 | $0.83 | |
Dosage: 5mg | ||||
360 pill | 5mg | $161.99 | $0.45 | |
180 pill | 5mg | $93.99 | $0.52 | |
120 pill | 5mg | $65.99 | $0.55 | |
90 pill | 5mg | $51.99 | $0.58 | |
60 pill | 5mg | $35.99 | $0.60 | |
30 pill | 5mg | $20.99 | $0.70 |
Glibenclamide Description
Overview of Glibenclamide
Glibenclamide, also known as glyburide in some regions, is an oral medication primarily used to manage type 2 diabetes mellitus. It belongs to the class of drugs called sulfonylureas, which work by stimulating the pancreas to produce more insulin. This increased insulin output helps to lower blood glucose levels and maintain better control over the disease. Glibenclamide has been a staple in diabetes management for many years, appreciated for its effectiveness and affordability.
Effectiveness and Benefits
Glibenclamide is known for its rapid onset of action, often beginning to lower blood sugar within a few hours after intake. It is particularly beneficial for patients who have sufficient pancreatic beta-cell function. Many users report significant improvements in their glycemic control after consistent use. Additionally, the medication can help reduce the risk of long-term complications associated with diabetes, such as nerve damage, kidney issues, and cardiovascular problems. Due to its longstanding presence on the market, clinicians have a good understanding of its efficacy and dosing protocols.
Possible Side Effects and Risks
While Glibenclamide is generally well-tolerated, it can cause side effects. The most common is hypoglycemia, which occurs when blood sugar drops too low, especially if doses are not properly managed or combined with excessive alcohol intake, unusual physical activity, or missed meals. Other potential side effects include weight gain, nausea, and gastrointestinal discomfort. Rarely, some patients may experience allergic reactions or skin rashes. It is important for users to monitor their blood glucose levels regularly and consult their healthcare provider if they notice any adverse symptoms.
Precautions and Interactions
Before starting Glibenclamide, patients should inform their doctor about any existing medical conditions, particularly liver or kidney problems, as these can affect how the medication is processed. It is also crucial to disclose all other medicines being taken, since Glibenclamide can interact with other drugs, including antibiotics, antifungals, or other antidiabetic agents. Alcohol consumption should be limited, as it can increase the risk of hypoglycemia. Pregnant and breastfeeding women are advised to consult their healthcare providers, as the safety profile during pregnancy is not fully established.
Usage and Dosage
The typical starting dose of Glibenclamide varies depending on the patient's condition, but it generally begins with a low dose that is gradually increased under medical supervision. It is usually taken once or twice daily, with meals to help reduce gastrointestinal discomfort and to stabilize blood sugar levels. Consistency in dosing and adherence to medical advice are critical for achieving optimal results and minimizing side effects. Patients are encouraged to regularly monitor their blood glucose and attend follow-up appointments to adjust doses if necessary.
Conclusion
Glibenclamide remains a widely used and effective medication for managing type 2 diabetes. Its ability to stimulate insulin production makes it a practical choice for many patients, especially those with residual pancreatic function. However, it requires careful monitoring due to the risk of hypoglycemia and other side effects. Proper adherence to prescribed doses, lifestyle modifications, and regular medical consultations are essential for safe and successful treatment outcomes. As with all medications, individual responses may vary, and ongoing medical guidance is vital to ensure optimal control of blood sugar levels.