Package | Dosage | Price | Price per Dose | |
---|---|---|---|---|
Dosage: 1% | ||||
5 tube | 1% | $50.99 | $10.20 | |
4 tube | 1% | $47.99 | $12.00 | |
3 tube | 1% | $41.99 | $14.00 | |
2 tube | 1% | $31.99 | $15.99 | |
Dosage: 5% | ||||
5 tube | 5% | $124.99 | $25.00 | |
4 tube | 5% | $107.99 | $27.00 | |
3 tube | 5% | $89.99 | $30.00 | |
2 tube | 5% | $69.99 | $34.99 |

Fluorouracil Description
Introduction to Fluorouracil
Fluorouracil, often referred to by its abbreviation 5-FU, is a chemotherapy medication commonly used in the treatment of various cancers. It belongs to the class of drugs known as antimetabolites, which work by interfering with the growth and division of cancer cells. This medication is typically prescribed under strict medical supervision and is administered in hospitals, clinics, or specialized oncology centers. Its primary purpose is to inhibit the synthesis of DNA and RNA in rapidly dividing cells, thus halting tumor progression.
Uses and Medical Applications
Fluorouracil is primarily used to treat cancers of the colon, rectum, stomach, pancreas, and breast. It can also be applied topically for certain skin conditions such as actinic keratosis or superficial basal cell carcinoma. In chemotherapy regimens, Fluorouracil is often combined with other agents to improve its efficacy and reduce side effects. The medication may be administered through various routes, including intravenous infusion, topical application, or intratumoral injection, depending on the form and treatment plan prescribed by a healthcare professional.
Mechanism of Action
The active ingredient in Fluorouracil mimics natural pyrimidine nucleotides, specifically uracil, which is a building block of RNA. When incorporated into cancer cells, it disrupts normal nucleotide synthesis, leading to defective DNA and RNA formation. This disruption causes apoptosis, or programmed cell death, particularly in cells that are dividing rapidly. Because healthy cells also undergo division, some side effects are inevitable, but cancer cells are generally more affected due to their faster growth rate.
Potential Side Effects and Precautions
Like all chemotherapeutic agents, Fluorouracil can cause a range of side effects. Common adverse reactions include nausea, vomiting, diarrhea, mouth sores, and skin reactions such as redness or rash. Some patients may experience hair loss or a lowered blood cell count, which can increase the risk of infections and bleeding. Serious but less common side effects include heart problems, liver toxicity, or neurological symptoms. It is essential for patients to undergo regular monitoring during treatment. Before starting therapy, patients should inform their healthcare provider about any allergies, existing health conditions, or medications they are taking to avoid interactions and complications.
Administration and Dosage
The dosage of Fluorouracil varies depending on the type of cancer, the treatment regimen, and the patient's overall health. It is usually given as an injection into a vein over a specific period or as a topical cream applied to the skin. Healthcare providers carefully calculate and adjust doses to optimize effectiveness while minimizing side effects. Patients are advised to follow all instructions strictly and report any adverse reactions promptly. In some cases, supportive medication may be given alongside to manage side effects such as nausea or immune suppression.
Storage and Handling
The medication should be stored in a secure, refrigerator-safe container, away from direct sunlight, and out of reach of children. Handling Fluorouracil requires caution to prevent accidental exposure, especially in its injectable form. Healthcare providers and patients should follow proper disposal procedures for unused medication or contaminated materials to avoid unintentional exposure. Patients receiving topical formulations should wash their hands thoroughly after application and avoid contact with eyes or mucous membranes.
Consultation and Professional Guidance
Fluorouracil is a potent chemotherapeutic drug that must be used under strict medical guidance. Self-medication is strongly discouraged due to the risk of severe side effects and dosing errors. Regular check-ups and laboratory tests are vital to assess treatment response and detect any early signs of toxicity. Always discuss any concerns, side effects, or changes in health with your healthcare provider. These professionals can provide personalized advice, ensure proper administration, and adjust treatment as needed to achieve the best possible outcomes.