
Package | Dosage | Price | Price per Dose | |
---|---|---|---|---|
Dosage: 500/15mg | ||||
180 pill | 500/15mg | $384.38 | $2.14 | |
120 pill | 500/15mg | $271.13 | $2.26 | |
90 pill | 500/15mg | $215.31 | $2.39 | |
60 pill | 500/15mg | $148.32 | $2.47 | |
30 pill | 500/15mg | $79.73 | $2.66 |
Actoplus Met Description
What is Actoplus Met?
Actoplus Met is a prescription medicine used by adults with type 2 diabetes to improve blood sugar control. It combines metformin, a medication that lowers sugar produced by the liver and improves insulin sensitivity, with pioglitazone, which makes body tissues respond better to insulin. In the United States you may see Actoplus Met or Actoplus Met XR listed. It is not for type 1 diabetes or for treating diabetic ketoacidosis. It should be used along with diet, exercise, and regular glucose monitoring as advised by your doctor. When you order online, a licensed US pharmacy will require a valid prescription and patient information to verify your order. Always confirm the exact product name, strength, and manufacturer to avoid substitutes or counterfeit pills.
How Actoplus Met helps manage diabetes
The metformin component lowers glucose production in the liver and helps muscles respond better to insulin. Pioglitazone reduces insulin resistance, improving glucose uptake in fat and muscle tissue. Together, these actions can lower fasting and postmeal glucose levels and may help reduce HbA1c over time. Some people report steadier readings when their regimen includes Actoplus Met as part of a broader diabetes plan. Your doctor will consider your overall health, kidney function, and other medicines before starting this fixed‑dose combination.
How to take Actoplus Met
Actoplus Met is usually taken once daily with a meal. Do not crush or chew extended‑release tablets. Swallow the tablet whole with water. The exact dose and whether you take it in the morning or evening are decided by your prescriber. If you miss a dose, take it with your next meal unless your clinician tells you otherwise. Do not double up doses to make up for a forgotten one. If you have any trouble tolerating the medicine, contact your pharmacist or doctor for guidance.
What to expect and common side effects
Common side effects include stomach upset, diarrhea, and a change in taste. Some people gain weight or feel more tired. Edema, or swelling in the ankles and feet, may occur with pioglitazone. Metformin can cause gastrointestinal symptoms that often improve after a few weeks if you take it with meals. More serious but rare risks include heart failure with fluid retention, liver problems, and a possible increased risk of bladder cancer. Seek medical attention promptly if you experience severe swelling, shortness of breath, yellowing of the skin or eyes, persistent vomiting, or severe abdominal pain.
Safety and warnings in the USA
Actoplus Met should not be used in people with significant kidney or liver disease, or in those who have a history of bladder cancer or active bladder cancer symptoms. It is generally avoided in people with heart failure that requires treatment or symptoms of fluid overload. The metformin part carries a rare risk of lactic acidosis, especially in kidney impairment, dehydration, or very heavy alcohol use. Regular blood tests are often needed to monitor kidney function, liver enzymes, and blood sugar levels. Always inform your doctor about all medications you take, including over‑the‑counter drugs and supplements, to avoid interactions.
Buying Actoplus Met online in the USA
When ordering online from a USA‑licensed pharmacy, you will need a valid prescription and current personal information. Check that the product is Actoplus Met (or Actoplus Met XR) with the correct strength and the right manufacturer. Read the label and packaging carefully, and store the medicine at room temperature as directed. Use reputable online pharmacies that require pharmacist review and provide a way to contact a licensed pharmacist with questions. Be vigilant for counterfeit products and never substitute Actoplus Met with another pioglitazone/metformin product without professional guidance. Insurance coverage and out‑of‑pocket costs vary, so ask about discounts or patient assistance if needed.
Should you discuss Actoplus Met with your doctor?
Yes. Your clinician will review your kidney and liver function, heart health, and other diabetes medicines before starting Actoplus Met. Tell them about any history of heart failure, liver problems, bladder issues, or alcohol use. If you are pregnant or breastfeeding, do not use this medicine unless your doctor approves. Regular follow‑ups and blood tests help ensure the therapy is working and safe for you. If you experience unusual symptoms or signs of low blood sugar, contact your provider promptly.